Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy
It is proposed that overexpression of P-glycoprotein (P-gp), encoded by the ABC subfamily B member 1 (ABCB1) gene, is involved in resistance to antiepileptic drugs (AEDs) in about 30 of patients with epilepsy. Genetic variation and haplotype patterns are population specific which may cause different...
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Main Authors: | Haerian, B.S., Lim, K.S., Mohamed, E.H.M., Tan, H.J., Tan, C.T., Raymond, A.A., Wong, C.P., Wong, S.W., Mohamed, Z. |
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Format: | Article |
Language: | English |
Published: |
2011
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Subjects: | |
Online Access: | http://eprints.um.edu.my/5080/1/Haerian-2011-Lack_of_association.pdf http://eprints.um.edu.my/5080/ |
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