Polymorphisms in methylenetetrahydrofolate reductase gene and risk of non-Hodgkin lymphoma in a multi-ethnic population

• Main Authors: Sujatha, S., Gan, G.G., Zain, S.M., Haerian, B.S., Bee, P.C., Lian, L.H., Chang, K.M., Ong, T.C., Mohamed, Z.
• Format: Article
• Language: English
• Published: Nature Publishing Group 2014
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/10056/1/00005617_105899.pdf; http://eprints.um.edu.my/10056/

An imbalance in folate metabolism can adversely affect DNA synthesis and methylation systems which can lead to susceptibility to non-Hodgkin lymphoma (NHL). Whether single nucleotide polymorphisms (SNPs) and their haplotypes in the methylenetetrahydrofolate reductase (MTHFR) are associated with NHL...