Lack of association of ABCB1 and PXR polymorphisms with response to treatment in epilepsy
It is proposed that overexpression of P-glycoprotein (P-gp), encoded by the ABC subfamily B member 1 (ABCB1) gene, is involved in resistance to antiepileptic drugs (AEDs) in about 30 of patients with epilepsy. Genetic variation and haplotype patterns are population specific which may cause different...
Saved in:
Main Authors: | , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
2011
|
Subjects: | |
Online Access: | http://eprints.um.edu.my/5080/1/Haerian-2011-Lack_of_association.pdf http://eprints.um.edu.my/5080/ |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|