Mitochondrial dysfunction in Down Syndrome: from pathology to therapy
Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. The...
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Main Authors: | Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023
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Online Access: | http://psasir.upm.edu.my/id/eprint/109511/1/1-s2.0-S0306452222006030-main.pdf http://psasir.upm.edu.my/id/eprint/109511/ https://linkinghub.elsevier.com/retrieve/pii/S0306452222006030 |
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