Targeted drug delivery to the brain via intranasal nanoemulsion: available proof of concept and existing challenges
Intranasal delivery has shown to circumvent blood-brain-barrier (BBB) and deliver the drugs into the CNS at a higher rate and extent than other conventional routes. The mechanism of drug transport from nose-to-brain is not fully understood yet, but several neuronal pathways are considered to be invo...
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Main Authors: | Chatterjee, Bappaditya, Gorain, Bapi, Mohananaidu, Keithanchali, Sengupta, Pinaki Ranjan, Mandal, Uttam Kumar, Choudhury, Hira |
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Format: | Article |
Language: | English English English |
Published: |
10.1016/j.ijpharm.2019.05.032
2019
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Subjects: | |
Online Access: | http://irep.iium.edu.my/79809/1/79809_Targeted%20drug%20delivery.pdf http://irep.iium.edu.my/79809/2/79809_Targeted%20drug%20delivery_SCOPUS.pdf http://irep.iium.edu.my/79809/3/79809_Targeted%20drug%20delivery_WOS.pdf http://irep.iium.edu.my/79809/ https://www.sciencedirect.com/science/article/pii/S0378517319303862?via%3Dihub#! |
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