The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation
Increased airway smooth muscle (ASM) mass is a prominent hallmark of airway remodeling in asthma. Inhaled corticosteroids and long-acting beta2-agonists remain the mainstay of asthma therapy, however are not curative and ineffective in attenuating airway remodeling. The geranyl acetophenone 2,4,6-tr...
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Main Authors: | Yap, Hui Min, Lee, Yu Zhao, Harith, Hanis Hazeera, Tham, Chau Ling, Cheema, Manraj Singh, Shaari, Khozirah, Israf Ali, Daud Ahmad |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018
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Online Access: | http://psasir.upm.edu.my/id/eprint/74185/1/The%20geranyl%20acetophenone%20tHGA%20attenuates%20human%20bronchial%20smooth%20muscle%20proliferation%20via%20inhibition%20of%20AKT%20phosphorylation.pdf http://psasir.upm.edu.my/id/eprint/74185/ https://www.nature.com/articles/s41598-018-34847-0.pdf |
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