Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells
Objectives Suramin is a polysulfonated naphthylurea with antiparasitic and potential antineoplastic activity. Suramin’s pharmacological actions, which have not yet been fully elucidated, include antagonism of the action of platelet-derived growth factor (PDGF) at its receptor. We investigated the...
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Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013
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Subjects: | |
Online Access: | http://irep.iium.edu.my/55280/1/7.%20Little-2013-Suramin%20inhibits%20PDGF-stimulated%20r.pdf http://irep.iium.edu.my/55280/ http://onlinelibrary.wiley.com/doi/10.1111/jphp.12064/abstract |
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