Mast cell stabilizing effect of a geranyl acetophenone in dengue virus infection using in vitro model of DENV3-induced RBL-2H3 cells

• Main Authors: Tan, Ji Wei, Wan Zahidi, Nuha Fahimah, Siew, Audrey Foong Kow, Soo, Kuan Meng, Shaari, Khozirah, Ahmad Israf, Daud, Chee, Hui Yee, Tham, Chau Ling
• Format: Article
• Language: English
• Published: Portland Press 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/81291/1/CELL.pdf; http://psasir.upm.edu.my/id/eprint/81291/; https://pubmed.ncbi.nlm.nih.gov/31110077/

Mast cells (MCs), a type of immune effector cell, have recently become recognized for their ability to cause vascular leakage during dengue virus (DENV) infection. Although MC stabilizers have been reported to attenuate DENV induced infection in animal studies, there are limited in vitro studies on...