Strategies to improve the physicochemical properties of peptide‑based drugs
Peptides are a rapid-growing class of therapeutics with unique and desirable physicochemical properties. Due to disadvantages such as low membrane permeability and susceptibility to proteolytic degradation, peptide-based drugs have limited bioavailability, a short half-life, and rapid in vivo elimin...
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Main Authors: | Lee, Michelle Felicia *, Poh, Chit Laa * |
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Format: | Article |
Published: |
Springer
2023
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Subjects: | |
Online Access: | http://eprints.sunway.edu.my/2159/ https://link.springer.com/article/10.1007/s11095-023-03486-0 |
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