Neural differentiation of human pluripotent stem cells for nontherapeutic applications: Toxicology, pharmacology, and in vitro disease modelling [Review article].

• Main Authors: Yap, May Shin *, Nathan, Kavitha R. *, Yeo, Yin *, Lim, Lee Wei, Poh, Chit Laa *, Richards, Mark, Lim, Wei Ling *, Othman, Lekhsan, Heng, Alexis Boon Chin *
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2015
• Subjects: RM Therapeutics. Pharmacology
• Online Access: http://eprints.sunway.edu.my/395/1/Neural%20Differentiation%20of%20Human%20Pluripotent%20Stem%20Cells.pdf; http://eprints.sunway.edu.my/395/; http://dx.doi.org/10.1155/2015/105172

Human pluripotent stem cells (hPSCs) derived from either blastocyst stage embryos (hESCs) or reprogrammed somatic cells (iPSCs) can provide an abundant source of human neuronal lineages that were previously sourced from human cadavers, abortuses, and discarded surgical waste. In addition to the well...