Rational drug discovery: Ellagic acid as a potent dual-target inhibitor against hepatitis C virus genotype 3 (HCV G3) NS3 enzymes

Structure-based virtual screening (SBVS) has served as a popular strategy for rational drug discovery. In this study, we aimed to discover novel benzopyran-based inhibitors that targeted the NS3 enzymes (NS3/4A protease and NS3 helicase) of HCV G3 using a combination of in silico and in vitro approa...

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Bibliographic Details
Main Authors: Lim, See Khai, Othman, Rozana, Yusof, Rohana, Heh, Choon Han
Format: Article
Published: Wiley 2021
Subjects:
Online Access:http://eprints.um.edu.my/26655/
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