Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells
New 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed using the 3D-QSAR model developed earlier. These compounds were prepared and their antiproliferative activity was evaluated against three breast cancer cell lines (MDA-MB231, SKBR-3 and MCF-7) and non-cancerous MCF-10A epithelial breast cell...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Royal Society of Chemistry
2020
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| Subjects: | |
| Online Access: | http://eprints.sunway.edu.my/1329/1/Tiekink%20RSC%20Adv%202020%2010%2025517.pdf http://eprints.sunway.edu.my/1329/ http://doi.org/10.1039/d0ra04970k |
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