The growth suppressing effects of Girinimbine on Hepg2 involve induction of apoptosis and cell cycle arrest.
Murraya koenigii is an edible herb widely used in folk medicine. Here we report that girinimbine, a carbazole alkaloid isolated from this plant, inhibited the growth and induced apoptosis in human hepatocellular carcinoma, HepG2 cells. The MTT and LDH assay results showed that girinimbine decreased...
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Main Authors: | Syam, Suvitha, Abdul, Ahmad Bustamam, Md.Sukari, Mohd. Aspollah, Mohan, Syam, Abdelwahab, Siddig Ibrahim, Tang , Sook Wah |
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Format: | Article |
Language: | English |
Published: |
MDPI
2011
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Online Access: | http://psasir.upm.edu.my/id/eprint/24911/ http://www.mdpi.com/ |
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