Discovery of small molecule inhibitors against the NS3/4A serine protease of Hepatitis C virus genotype 3 via high-throughput virtual screening and in vitro evaluations
The hepatitis C virus (HCV) consists of eight genotypes and 90 subtypes, with genotype (GT) 3 being the second most common globally and is linked to higher incidences of steatosis and rapid development of fibrosis and cirrhosis. The NS3/4A serine protease, a heterodimer complex of two HCV non-struct...
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Main Authors: | Sakhor, W., Teoh, T. C., Yusof, R., Lim, S. K., Razif, M. F. M. |
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Format: | Article |
Published: |
Malaysian Society for Parasitology
2020
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Online Access: | http://eprints.um.edu.my/36458/ |
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