Discovery of small molecule inhibitors against the NS3/4A serine protease of Hepatitis C virus genotype 3 via high-throughput virtual screening and in vitro evaluations

The hepatitis C virus (HCV) consists of eight genotypes and 90 subtypes, with genotype (GT) 3 being the second most common globally and is linked to higher incidences of steatosis and rapid development of fibrosis and cirrhosis. The NS3/4A serine protease, a heterodimer complex of two HCV non-struct...

Full description

Saved in:
Bibliographic Details
Main Authors: Sakhor, W., Teoh, T. C., Yusof, R., Lim, S. K., Razif, M. F. M.
Format: Article
Published: Malaysian Society for Parasitology 2020
Subjects:
Online Access:http://eprints.um.edu.my/36458/
Tags: Add Tag
No Tags, Be the first to tag this record!