In-silico design of curcumin analogs as potential inhibitors of dengue virus NS2B/NS3 protease

• Main Authors: Roney, Miah, Huq, A. K. M. Moyeenul, Mohd Fadhlizil Fasihi, Mohd Aluwi, Saiful Nizam, Tajuddin
• Format: Article
• Language: English; English
• Published: World Scientific Publishing Co Pte Ltd 2023
• Subjects: Q Science (General); RA Public aspects of medicine
• Online Access: http://umpir.ump.edu.my/id/eprint/38177/1/In-silico%20design%20of%20curcumin%20analogs%20as%20potential%20inhibitors%20of%20dengue%20virus%20NS2B.pdf; http://umpir.ump.edu.my/id/eprint/38177/2/In-silico%20Design%20of%20Curcumin%20Analogs%20as%20Potential%20Inhibitors.pdf; http://umpir.ump.edu.my/id/eprint/38177/; https://doi.org/10.1142/S2737416523500321; https://doi.org/10.1142/S2737416523500321

Curcumin can interact with a variety of molecules implicated in a wide range of disorders. It can also hinder dengue virus’s (DENV’s) ability to infect cells. This work used computational analysis to identify and forecast the most potent curcumin analogs against the DENV NS2B/NS3 protease. In this s...