Analogues of 2 `-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase
A series of C4-substituted tertiary nitrogen-bearing 2 `-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2 `-hydroxychalcone analogues displayed a better inhibition against acetylcholinesterase (AChE) than butyrylcholinest...
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Main Authors: | Sukumaran, Sri Devi, Nasir, Shah Bakhtiar, Tee, Jia Ti, Buckle, Michael J. C., Othman, Rozana, Abd Rahman, Noorsaadah, Lee, Vannajan Sanghiran, Bukhari, Syed Nasir Abbas, Chee, Chin Fei |
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Format: | Article |
Published: |
Taylor & Francis Ltd
2021
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Online Access: | http://eprints.um.edu.my/34280/ |
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