2-Benzyloxynaphthalene aminoalkylated chalcone designed as acetylcholinesterase inhibitor: structural characterisation, in vitro biological activity and molecular docking studies

The design of an acetylcholinesterase inhibitor with multifunctional properties became the perspective for the development of an effective drug against Alzheimer's disease. Towards this target, 1-{4-hydroxy-3-[(piperidin-1-yl)methyl]phenyl}ethan-1-one (chalcone 3) was prepared and studied as an...

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Bibliographic Details
Main Authors: Aljohani, G., Ali, A. S., Said, M. A., Hughes, D. L., Alraqa, S. Y., Amran, S., Ahmad, F., Basar, N.
Format: Article
Published: Elsevier B.V. 2020
Subjects:
Online Access:http://eprints.utm.my/id/eprint/92899/
http://dx.doi.org/10.1016/j.molstruc.2020.128898
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