Autophagy is deregulated in cancer-associated fibroblasts from oral cancer and is stimulated during the induction of fibroblast senescence by TGF-beta 1
Many of the characteristics ascribed to cancer-associated fibroblasts (CAFs) are shared by activated, autophagic and senescent fibroblasts. Whilst most oral squamous cell carcinomas (OSCCs) are genetically unstable (GU-OSCC), genetically stable variants (GS-OSCC) have been described and, notably, CA...
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Main Authors: | Tan, May Leng, Parkinson, E. Kenneth, Yap, Lee Fah, Paterson, Ian C. |
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Format: | Article |
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Nature Research
2021
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Online Access: | http://eprints.um.edu.my/26393/ |
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