Autophagy is deregulated in cancer-associated fibroblasts from oral cancer and is stimulated during the induction of fibroblast senescence by TGF-beta 1

Many of the characteristics ascribed to cancer-associated fibroblasts (CAFs) are shared by activated, autophagic and senescent fibroblasts. Whilst most oral squamous cell carcinomas (OSCCs) are genetically unstable (GU-OSCC), genetically stable variants (GS-OSCC) have been described and, notably, CA...

Full description

Saved in:
Bibliographic Details
Main Authors: Tan, May Leng, Parkinson, E. Kenneth, Yap, Lee Fah, Paterson, Ian C.
Format: Article
Published: Nature Research 2021
Subjects:
Online Access:http://eprints.um.edu.my/26393/
Tags: Add Tag
No Tags, Be the first to tag this record!