Fibroblast growth factor receptor 4 (FGF4) and fibroblast growth factor 19 (FGFR19) autocrine enhance brest cancer cells survival

• Main Authors: Tiong, Kai Hung, Tan, Boon Shing, Choo, Heng Lungh, Chung, Felicia Fei-Lei, Hii, Ling Wei, Tan, Si Hoey, Khor, Nelson Tze Woei, Wong, Shew Fung, See, Sze Jia, Tan, Yuen Fen, Rosli, Rozita, Cheong, Soon Keng, Leong, Chee Onn
• Format: Article
• Language: English
• Published: Impact Journals LLC 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/54313/1/Fibroblast%20growth%20factor%20%20receptor%204.pdf; http://psasir.upm.edu.my/id/eprint/54313/; http://europepmc.org/abstract/pmc/pmc5295378

Basal-like breast cancer is an aggressive tumor subtype with poor prognosis. The discovery of underlying mechanisms mediating tumor cell survival, and the development of novel agents to target these pathways, is a priority for patients with basal-like breast cancer. From a functional screen to ident...