Anti-tumor activity of metformin in human epidermal growth factor receptor 2 positive breast cancer cells

• Main Authors: Huda, Fathul, Sari Ekawati,, Anindy Putri Addina,, Ahmad Faried,, Berbudi, Afiat, Rusdiana, Taofik, Tenny Putri,, Nurul Qomarilla,, Hilfi, Lukman, Setiawan, Iwan, Bashari, Muhammad Hasan
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2021
• Online Access: http://journalarticle.ukm.my/17415/1/18.pdf; http://journalarticle.ukm.my/17415/; https://www.ukm.my/jsm/malay_journals/jilid50bil5_2021/KandunganJilid50Bil5_2021.html

Breast Cancer (BC) is the leading cause of cancer death in women. One BC subtype is very aggressive with amplification of human epidermal growth factor receptor 2 (HER2) protein. Although specific HER2+ targeting agents are available, most of HER2+ BC patients develop resistant to these agents....