Epithelial-to-mesenchymal transition (EMT) causing acquired resistance to afatinib in a patient with epidermal growth factor receptor (EGFR)-mutant lung adenocarcinoma
We report the first case of epithelial-to-mesenchymal transition (EMT) as the cause of acquired resistance to the second-generation EGFR-tyrosine kinase inhibitor (TKI), afatinib in a patient with advanced non-small cell lung cancer (NSCLC) harboring a sensitizing EGFR mutation. Patients with EGFR...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
AME Publishing Company
2018
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| Subjects: | |
| Online Access: | http://ir.unimas.my/id/eprint/22818/1/Chai%2C%20Chee%20Shee.pdf http://ir.unimas.my/id/eprint/22818/ http://jtd.amegroups.com/search/advancedResults |
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