In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking
Glioblastoma multiforme (GBM) is a high-grade brain tumor of which the survival patients remain poor. Tousled-like kinase 1 (TLK1), a serine-threonine kinase, was identified to be overexpressed in cancers such as GBM. TLK1 plays an important role in controlling survival pathways. To date, there is n...
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Main Authors: | Kamariah Ibrahim,, Abubakar Danjuma Abdullahi,, Nor Azian Abdul Murad,, Roslan Harun,, Rahman Jamal, |
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Format: | Article |
Language: | English |
Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2018
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Online Access: | http://journalarticle.ukm.my/13245/1/38-134-1-PB.pdf http://journalarticle.ukm.my/13245/ http://spaj.ukm.my/apjmm/index.php/apjmm/issue/view/18 |
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