Evaluation of potential bacterial protease inhibitor properties of selected hydroxyquinoline derivatives: an in silico docking and molecular dynamics simulation approach

• Main Authors: Riaz, Faiza, Hossain, Md. Sanower, Roney, Miah, Ali, Yousaf, Qureshi, Saira, Muhammad, Riaz, Moshawih, Said, Abd Hamid, Shafida, Seidel, Veronique, Rashid, Haroon ur, Ming, Long Chiau
• Format: Article
• Language: English
• Published: Taylor & Francis 2022
• Subjects: QD Chemistry; RM Therapeutics. Pharmacology; RM300 Drugs and their action
• Online Access: http://irep.iium.edu.my/101467/1/101467_Evaluation%20of%20potential%20bacterial%20protease%20inhibitor%20properties_In%20Press.pdf; http://irep.iium.edu.my/101467/; https://www.tandfonline.com/doi/full/10.1080/07391102.2022.2146200

Antimicrobial drug resistance (AMR) is a severe global threat to public health. The increasing emergence of drug-resistant bacteria requires the discovery of novel antibacterial agents. Quinoline derivatives have previously been reported to exhibit antimalarial, antiviral, antitumor, antiulcer, anti...