In silico discovery of potential uridine-cytidine kinase 2 inhibitors form the rhizome of Alpina mutica

• Main Authors: Malami, Ibrahim, Abdul, Ahmad Bustamam, Abdullah, Rasedee, Kassim, Nur Kartinee, Waziri, Peter M., Etti, Imaobong Christopher
• Format: Article
• Language: English
• Published: M D P I AG 2016
• Online Access: http://psasir.upm.edu.my/id/eprint/54529/1/In%20silico%20discovery%20of%20potential%20uridine-cytidine%20kinase%202%20inhibitors%20form%20the%20rhizome%20of%20Alpina%20mutica.pdf; http://psasir.upm.edu.my/id/eprint/54529/; http://www.mdpi.com/1420-3049/21/4/417

Uridine-cytidine kinase 2 is implicated in uncontrolled proliferation of abnormal cells and it is a hallmark of cancer, therefore, there is need for effective inhibitors of this key enzyme. In this study, we employed the used of in silico studies to find effective UCK2 inhibitors of natural origin u...