H-1 NMR-based metabolomics investigation of copper-laden rat: a model of Wilson's disease
Wilson's disease (WD), also known as hepatoleticular degeneration (HLD), is a rare autosomal recessive genetic disorder of copper metabolism, which causes copper to accumulate in body tissues. In this study, rats fed with copper-laden diet are used to render the clinical manifestations of WD, a...
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Main Authors: | Xu, Jingjing, Jiang, Huaizhou, Li, Jinquan, Cheng, Kian-Kai, Dong, Jiyang, Chen, Zhong |
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Format: | Article |
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Public Library of Science
2015
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Online Access: | http://eprints.utm.my/id/eprint/55541/ http://dx.doi.org/10.1371/journal.pone.0119654 |
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