H-1 NMR-based metabolomics investigation of copper-laden rat: a model of Wilson's disease

Wilson's disease (WD), also known as hepatoleticular degeneration (HLD), is a rare autosomal recessive genetic disorder of copper metabolism, which causes copper to accumulate in body tissues. In this study, rats fed with copper-laden diet are used to render the clinical manifestations of WD, a...

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Bibliographic Details
Main Authors: Xu, Jingjing, Jiang, Huaizhou, Li, Jinquan, Cheng, Kian-Kai, Dong, Jiyang, Chen, Zhong
Format: Article
Published: Public Library of Science 2015
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Online Access:http://eprints.utm.my/id/eprint/55541/
http://dx.doi.org/10.1371/journal.pone.0119654
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