Diarylpentanoid (1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one) (MS13) exhibits anti-proliferative, apoptosis induction and anti-migration properties on androgen-independent human prostate cancer by targeting cell cycle-apoptosis and PI3K signalling pathways
Diarylpentanoids exhibit a high degree of anti-cancer activity and stability in vitro over curcumin in prostate cancer cells. Hence, this study aims to investigate the effects of a diarylpentanoid, 1,5-bis(4-hydroxy-3-methoxyphenyl)-1,4-pentadiene-3-one (MS13) on cytotoxicity, anti-proliferative, ap...
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Main Authors: | Abd Wahab, Nurul Azwa, Abas, Faridah, Othman, Iekhsan, Naidu, Rakesh |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media
2021
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Online Access: | http://psasir.upm.edu.my/id/eprint/96718/1/ABSTRACT.pdf http://psasir.upm.edu.my/id/eprint/96718/ https://www.frontiersin.org/articles/10.3389/fphar.2021.707335/full |
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