Synthesis of new 1,2-disubstituted benzimidazole analogs as potent inhibitors of Î-Glucuronidase and in silico study
New benzimidazole analogues (1–18) were synthesized and characterized through different spectroscopic techniques such as 1H NMR, 13C NMR and HREI-MS. All analogues were screened for β-glucuronidase inhibitory potential. All analogues showed varied degree of inhibitory potentials with IC50 values ran...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Published: |
Elsevier B.V.
2021
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| Online Access: | http://psasir.upm.edu.my/id/eprint/95271/ https://www.sciencedirect.com/science/article/pii/S1878535221005207?via%3Dihub |
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