Ethanol induces microglial cell death via the NOX/ROS/PARP/TRPM2 signalling pathway

• Main Authors: Sha’fie, Muhammad Syahreel Azhad, Rathakrishnan, Sharani, Hazanol, Iffa Nadhira, Mohd Dali, Mohd Haziq Izzazuddin, Khayat, Mohd Ezuan, Ahmad, Syahida, Hussin, Yazmin, Alitheen, Noorjahan Banu, Jiang, Lin Hua, Syed Mortadza, Sharifah Alawieyah
• Format: Article
• Language: English
• Published: Multidisciplinary Digital Publishing Institute 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/88851/1/ABSTRACT.pdf; http://psasir.upm.edu.my/id/eprint/88851/; https://www.mdpi.com/2076-3921/9/12/1253

Microglial cells are the primary immune cell resident in the brain. Growing evidence indicates that microglial cells play a prominent role in alcohol-induced brain pathologies. However, alcohol-induced effects on microglial cells and the underlying mechanisms are not fully understood, and evidence e...