Combining PARP inhibition with platinum, ruthenium or gold complexes for cancer therapy
Platinum drugs are heavily used first-line chemotherapeutic agents for many solid tumours and have stimulated substantial interest in the biological activity of DNA-binding metal complexes. These complexes generate DNA lesions which trigger the activation of DNA damage response (DDR) pathways that a...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
John Wiley and Sons
2020
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| Online Access: | http://psasir.upm.edu.my/id/eprint/88194/1/ABSTRACT.pdf http://psasir.upm.edu.my/id/eprint/88194/ https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202000391 |
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