Gene transfer into the lung by nanoparticle dextran-spermine/plasmid DNA complexes.
A novel cationic polymer, dextran-spermine (D-SPM), has been found to mediate gene expression in a wide variety of cell lines and in vivo through systemic delivery. Here, we extended the observations by determining the optimal conditions for gene expression of D-SPM/plasmid DNA (D-SPM/pDNA) in cel...
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Main Authors: | Abdullah, Syahrilnizam, Wai Yeng, Wendy-Yeo, Hosseinkhani, Hossein, Hosseinkhani, Mohsen, Masrawa, Ehab, Ramasamy, Rajesh, Rosli, Rozita, Abdul Rahman, Sabariah, Domb, Abraham J. |
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Format: | Article |
Language: | English English |
Published: |
Hindawi Publishing Corporation
2010
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Online Access: | http://psasir.upm.edu.my/id/eprint/14867/1/Gene%20transfer%20into%20the%20lung%20by%20nanoparticle%20dextran.pdf http://psasir.upm.edu.my/id/eprint/14867/ http://www.hindawi.com/ |
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