Japanese encephalitis virus: Biological clones from a clinical isolate quasispecies show differing neurovirulence in vitro and in a mouse model
The Japanese encephalitis virus (JEV), a leading cause of encephalitis, exists as quasispecies in clinical isolates. Using a limiting dilution method combined with immunohistochemistry to detect viral antigens, 10 biological clones were isolated and purified from a clinical JEV isolate (CNS138/9) de...
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Main Authors: | Shu, Pin Yu, Kien, Chai Ong, Soon, Hao Tan, David, Perera, Kum, Thong Wong |
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Format: | Article |
Language: | English |
Published: |
2020
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Subjects: | |
Online Access: | http://ir.unimas.my/id/eprint/33498/1/Shu%20Pin%20Yu.pdf http://ir.unimas.my/id/eprint/33498/ https://www.neurology-asia.org/articles/neuroasia-2020-25(3)-279.pdf |
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