Evaluation of the effects of mitragyna speciosa alkaloid extract on cytochrome P450 enzymes using a high throughput assay
The extract from Mitragyna speciosa has been widely used as an opium substitute, mainly due to its morphine-like pharmacological effects. This study investigated the effects of M. speciosa alkaloid extract (MSE) on human recombinant cytochrome P450 (CYP) enzyme activities using a modified Crespi met...
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Main Authors: | Kong, W.M., Chik, Z., Ramachandra, M., Subramaniam, U., Aziddin, R.E.R., Mohamed, Z. |
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Format: | Article |
Language: | English |
Published: |
2011
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Subjects: | |
Online Access: | http://eprints.um.edu.my/5064/1/Kong-2011-Evaluation_of_the_Ef.pdf http://eprints.um.edu.my/5064/ |
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