Role of cytochrome P450 monooxygenase in the bioactivation of aflatoxin B1

• Main Authors: Sureeporn Nualkaew,, Hirun Saelim,, Danai Tiwawech,, Tanate Panrat Imran Parvez,, Amornrat Phongdara,
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2017
• Online Access: http://journalarticle.ukm.my/11376/1/19%20Sureeporn.pdf; http://journalarticle.ukm.my/11376/; http://www.ukm.my/jsm/english_journals/vol46num9_2017/contentsVol46num9_2017.html

In a previous study, the gene EgP450 that encodes the proteins of 505 amino acids was isolated from oil palm. The recombinant protein EgP450 is bound to phenylurea-like herbicides which detoxify the substance. Aflatoxin B1 (AFB1), a mycotoxin produced by Aspergillus sp., is another toxic compound th...