Antidepressant-like effect of mitragynine isolated from Mitragyna speciosa Korth in mice model of depression.

• Main Authors: Nasir, Farah Idayu, Baharuldin, Mohamad Taufik Hidayat, Mohd Moklas, Mohamad Aris, Fakurazi, Sharida, Adib Ridzuan, Nurul Raudzah, Abdul Rahman, Shamima, Apryani, Evhy
• Format: Article
• Language: English; English
• Published: Elsevier 2011
• Online Access: http://psasir.upm.edu.my/id/eprint/24452/1/Antidepressant-like%20effect%20of%20mitragynine%20.pdf; http://psasir.upm.edu.my/id/eprint/24452/; http://www.phytomedicinejournal.com/

Mitragyna speciosa Korth. leaves have been used for decades as a traditional medicine to treat diarrhea, diabetes and to improve blood circulation by natives of Malaysia, Thailand and other regions of Southeast Asia. Mitragynine is the major active alkaloid in the plant. To date, the role of mitragy...