Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression
Introduction: Morphine is an opioid prescribed to treat aches and pains. However, morphine often causes opioid-induced constipation (OIC). Aquaporin (AQP) transporters, especially AQP3 and AQP4, play an essential role in mediating constipation. Bisacodyl is a common laxative used to treat constipati...
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Main Authors: | Rahmadi, Mahardian, Ardianto, Chrismawan, Nurhan, Ahmad D., Chasanah, Rafiqa A., Krismonika, Dewi I., Puspitasari, Arina D., Suprapti, Budi, Segaran, Santhra, Phan, Chia Wei, Khotib, Junaidi |
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Format: | Article |
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Belgorod State National Research University
2022
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Online Access: | http://eprints.um.edu.my/44063/ |
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