Differentiation of osteoblasts: the links between essential transcription factors

• Main Authors: Khotib, Junaidi, Marhaeny, Honey Dzikry, Miatmoko, Andang, Budiatin, Aniek Setiya, Chrismawan, Ardianto, Rahmadi, Mahardian, Pratama, Yusuf Alif, Bakhtiar, M. Taher
• Format: Article
• Language: English
• Published: Taylor & Francis 2022
• Subjects: RS192 Materia Medica-Pharmaceutical Technology
• Online Access: http://irep.iium.edu.my/101462/1/101462_Differentiation%20of%20osteoblasts.pdf; http://irep.iium.edu.my/101462/; https://www.tandfonline.com/doi/full/10.1080/07391102.2022.2148749

Osteoblasts, cells derived from mesenchymal stem cells (MSCs) in the bone marrow, are cells responsible for bone formation and remodeling. The differentiation of osteoblasts from MSCs is triggered by the expression of specific genes, which are subsequently controlled by pro-osteogenic pathways. Mat...