Apoferritin-encapsulated jerantinine A for transferrin receptor targeting and enhanced selectivity in breast cancer therapy
The O-acetyl (or acetate) derivative of the Aspidosperma alkaloid Jerantinine A (JAa) elicits anti-tumor activity against cancer cell lines including mammary carcinoma cell lines irrespective of receptor status (0.14 < GI50 < 0.38 mu M), targeting microtubule dynamics. By exploiting breast can...
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Main Authors: | Abuzaid, Haneen, Abdelrazig, Salah, Ferreira, Lenny, Collins, Hilary M., Kim, Dong-Hyun, Lim, Kuan-Hon, Kam, Toh-Seok, Turyanska, Lyudmila, Bradshaw, Tracey D. |
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Format: | Article |
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American Chemical Society
2022
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Online Access: | http://eprints.um.edu.my/41924/ |
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