Over-expression of Runx1 transcription factor impairs the development of thymocytes from the double-negative to double-positive stages
Runx1 transcription factor is highly expressed at a CD4/CD8-double-negative (DN) stage of thymocyte development but is down-regulated when cells proceed to the double-positive (DP) stage. In the present study, we examined whether the down-regulation of Runx1 is necessary for thymocyte differentiatio...
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Main Authors: | , , , , , , , , , , , , , , , |
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Format: | Article |
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Blackwell Publishing
2010
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Subjects: | |
Online Access: | http://eprints.um.edu.my/13023/ http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2567.2009.03230.x/abstract http://www.ncbi.nlm.nih.gov/pubmed/20102410 |
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