Signalling pathways regulating galactosaminoglycan synthesis and structure in vascular smooth muscle: implications for lipoprotein binding and atherosclerosis
Atherosclerosis commences with the trapping of low density lipoproteins (LDLs) in blood vessels by modified proteoglycans (PGs) with hyperelongated glycosaminoglycan (GAG) chains. GAG chain synthesis and growth factor mediated hyperelongation regulates the composition and size of PGs in a manner tha...
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Main Authors: | Afroz, Rizwana, Cao, Yingnan, Rostam, Muhamad Ashraf, Ta, Hang, Xu, Suowen, Zheng, Wenhua, Osman, Narin, Kamato, Danielle, Little, Peter J. |
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Format: | Article |
Language: | English English English |
Published: |
Elsevier
2018
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Subjects: | |
Online Access: | http://irep.iium.edu.my/62249/1/62249_Signalling%20pathways%20regulating%20galactosaminoglycan.pdf http://irep.iium.edu.my/62249/2/62249_Signalling%20pathways%20regulating%20galactosaminoglycan_SCOPUS.pdf http://irep.iium.edu.my/62249/3/62249_Signalling%20pathways%20regulating%20galactosaminoglycan_WOS.pdf http://irep.iium.edu.my/62249/ https://doi.org/10.1016/j.pharmthera.2018.02.005 |
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