Sp1, Acetylated Histone-3 and p300 Regulate TRAIL Transcription: Mechanisms of PDGF-BB-mediated VSMC Proliferation and Migration

• Main Authors: Md Azahri, Nor Saadah, Di Bartolo, Belinda A, Khachigian, Levon M., Kavurma, Mary M.
• Format: Article
• Language: English; English
• Published: Wiley 2012
• Subjects: R Medicine (General)
• Online Access: http://irep.iium.edu.my/62009/1/62009_Sp1%2C%20Acetylated%20Histone-3%20and%20p300%20Regulate.pdf; http://irep.iium.edu.my/62009/2/62009_Sp1%2C%20Acetylated%20Histone-3%20and%20p300%20Regulate%20TRAIL_SCOPUS.pdf; http://irep.iium.edu.my/62009/; https://onlinelibrary.wiley.com/doi/10.1002/jcb.24135

We recently reported that TNF-related apoptosis-inducing ligand (TRAIL) is important in atherogenesis, since it can induce vascular smooth muscle cell (VSMC) proliferation and arterial thickening following injury. Here we show the first demonstrate that TRAIL siRNA reduces platelet-derived growth fa...