Antiproliferation effect of imatinib mesylate on MCF7, T-47D tumorigenic and MCF 10A nontumorigenic breast cell lines via PDGFR-β, PDGF-BB, c-Kit and SCF genes

• Main Authors: Kadivar, A., Kamalidehghan, B., Javar, H.A., Karimi, B., Sedghi, R., Noordin, M.I.
• Format: Article
• Published: Dove Medical Press 2017
• Subjects: R Medicine
• Online Access: http://eprints.um.edu.my/19150/; http://dx.doi.org/10.2147/DDDT.S124102

Recent cancer molecular therapies are targeting main functional molecules to control applicable process of cancer cells. Attractive targets are established by receptor tyrosine kinases, such as platelet-derived growth factor receptors (PDGFRs) and c-Kit as mostly irregular signaling, which is due to...