Development of volumetric absorptive microsampling for analysis phenytoin levels and its application to monitoring therapy in epilepsy patients
Phenytoin (PHT) is an anticonvulsant drug used as monotherapy or combination therapy to treat seizures. However, PHT has a narrow therapeutic index range of 10–20 μg/ml, so it is necessary to monitor drug levels. This study aims to obtain optimum sample preparation conditions and a validated analyti...
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Main Authors: | Mardhiani, Rizka, Harahap, Yahdiana, Wiratman, Winnugroho, Jaswir, Irwandi |
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Format: | Article |
Language: | English English |
Published: |
Open Science Publishers LLP
2023
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Subjects: | |
Online Access: | http://irep.iium.edu.my/109697/7/109697_Development%20of%20volumetric%20absorptive%20microsampling%20for%20analysis%20phenytoin.pdf http://irep.iium.edu.my/109697/8/109697_Development%20of%20volumetric%20absorptive%20microsampling%20for%20analysis%20phenytoin_Scopus.pdf http://irep.iium.edu.my/109697/ https://japsonline.com/abstract.php?article_id=4068&sts=2 http://dx.doi.org/10.7324/JAPS.2023.125948 |
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