A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by...
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Natural Product Incorporation
2017
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my.utm.769832018-04-30T14:30:33Z http://eprints.utm.my/id/eprint/76983/ A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) Jibril, S. Sirat, H. M. Basar, N. QD Chemistry A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by comparison of the spectral data with those previously reported in the literature. Compounds 10-13 were isolated from C. sieberiana for the first time. Compounds 1, 2 and 3 exhibited significant inhibitory activity on 15-lipoxygenase with IC50 values of 2.62, 1.27 and 0.98 ìM, respectively. Compounds 2 and 3 showed acetylcholinesterase inhibitory activity with IC50 values of 10.57 and 2.89 ìM, respectively. Natural Product Incorporation 2017 Article PeerReviewed Jibril, S. and Sirat, H. M. and Basar, N. (2017) A new stilbene from the root of cassia sieberiana D.C. (Fabaceae). Natural Product Communications, 12 (7). pp. 1095-1098. ISSN 1934-578X https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e |
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QD Chemistry Jibril, S. Sirat, H. M. Basar, N. A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
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A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by comparison of the spectral data with those previously reported in the literature. Compounds 10-13 were isolated from C. sieberiana for the first time. Compounds 1, 2 and 3 exhibited significant inhibitory activity on 15-lipoxygenase with IC50 values of 2.62, 1.27 and 0.98 ìM, respectively. Compounds 2 and 3 showed acetylcholinesterase inhibitory activity with IC50 values of 10.57 and 2.89 ìM, respectively. |
format |
Article |
author |
Jibril, S. Sirat, H. M. Basar, N. |
author_facet |
Jibril, S. Sirat, H. M. Basar, N. |
author_sort |
Jibril, S. |
title |
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
title_short |
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
title_full |
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
title_fullStr |
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
title_full_unstemmed |
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) |
title_sort |
new stilbene from the root of cassia sieberiana d.c. (fabaceae) |
publisher |
Natural Product Incorporation |
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2017 |
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http://eprints.utm.my/id/eprint/76983/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e |
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13.160551 |