A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)

A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by...

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Main Authors: Jibril, S., Sirat, H. M., Basar, N.
Format: Article
Published: Natural Product Incorporation 2017
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Online Access:http://eprints.utm.my/id/eprint/76983/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e
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spelling my.utm.769832018-04-30T14:30:33Z http://eprints.utm.my/id/eprint/76983/ A new stilbene from the root of cassia sieberiana D.C. (Fabaceae) Jibril, S. Sirat, H. M. Basar, N. QD Chemistry A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by comparison of the spectral data with those previously reported in the literature. Compounds 10-13 were isolated from C. sieberiana for the first time. Compounds 1, 2 and 3 exhibited significant inhibitory activity on 15-lipoxygenase with IC50 values of 2.62, 1.27 and 0.98 ìM, respectively. Compounds 2 and 3 showed acetylcholinesterase inhibitory activity with IC50 values of 10.57 and 2.89 ìM, respectively. Natural Product Incorporation 2017 Article PeerReviewed Jibril, S. and Sirat, H. M. and Basar, N. (2017) A new stilbene from the root of cassia sieberiana D.C. (Fabaceae). Natural Product Communications, 12 (7). pp. 1095-1098. ISSN 1934-578X https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QD Chemistry
spellingShingle QD Chemistry
Jibril, S.
Sirat, H. M.
Basar, N.
A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
description A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by comparison of the spectral data with those previously reported in the literature. Compounds 10-13 were isolated from C. sieberiana for the first time. Compounds 1, 2 and 3 exhibited significant inhibitory activity on 15-lipoxygenase with IC50 values of 2.62, 1.27 and 0.98 ìM, respectively. Compounds 2 and 3 showed acetylcholinesterase inhibitory activity with IC50 values of 10.57 and 2.89 ìM, respectively.
format Article
author Jibril, S.
Sirat, H. M.
Basar, N.
author_facet Jibril, S.
Sirat, H. M.
Basar, N.
author_sort Jibril, S.
title A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
title_short A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
title_full A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
title_fullStr A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
title_full_unstemmed A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
title_sort new stilbene from the root of cassia sieberiana d.c. (fabaceae)
publisher Natural Product Incorporation
publishDate 2017
url http://eprints.utm.my/id/eprint/76983/
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e
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score 13.160551