Bioassay-guided isolation of antioxidants and ?-Glucosidase inhibitors from the root of cassia sieberiana D.C. (fabaceae)

• Main Authors: Jibril, S., Sirat, H. M., Basar, N.
• Format: Article
• Language: English
• Published: ACG Publications 2017
• Subjects: QD Chemistry
• Online Access: http://eprints.utm.my/id/eprint/75725/1/HasnahMohdSirat_Bioassay-GuidedIsolationofAntioxidantsanda-Glucosidase.pdf; http://eprints.utm.my/id/eprint/75725/; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85020407947&partnerID=40&md5=d82667dd644d6e6a0519e8f0108cdbd0

Bioassay-guided isolation was used to investigate the antioxidants and α-glucosidase inhibitors from extract of root of Cassia sieberiana. The ethyl acetate fraction demonstrated strong free radical scavenging (DPPH and ABTS+) and potent α-glucosidase inhibition. The subsequent fractionation and pur...