A new stilbene from the root of cassia sieberiana D.C. (Fabaceae)
A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by...
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| Main Authors: | , , |
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| Format: | Article |
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Natural Product Incorporation
2017
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| Online Access: | http://eprints.utm.my/id/eprint/76983/ https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026488910&partnerID=40&md5=f8b3ae723dec500e9879e33f1e54523e |
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| Summary: | A new stilbene (1) was isolated from the root of Cassia sieberiana D. C. together with thirteen known compounds, one stilbene (2), three flavonoids (3-5), six anthraquinones (6-11), two triterpenes (12-13), and phytosterol (14). Their structures were identified using spectroscopic techniques and by comparison of the spectral data with those previously reported in the literature. Compounds 10-13 were isolated from C. sieberiana for the first time. Compounds 1, 2 and 3 exhibited significant inhibitory activity on 15-lipoxygenase with IC50 values of 2.62, 1.27 and 0.98 ìM, respectively. Compounds 2 and 3 showed acetylcholinesterase inhibitory activity with IC50 values of 10.57 and 2.89 ìM, respectively. |
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