Discovery of novel Coumarin-Schiff base hybrids as potential acetylcholinesterase inhibitors: design, synthesis, enzyme inhibition, and computational studies
To discover anti-acetylcholinesterase agents for the treatment of Alzheimer’s disease (AD), a series of novel Schiff base-coumarin hybrids was rationally designed, synthesized successfully, and structurally characterized using Fourier transform infrared (FTIR), Nuclear magnetic resonance (NMR), and...
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Main Authors: | Hasan, Aso Hameed, Abdulrahman, Faruq Azeez, Obaidullah, Ahmad J., Alotaibi, Hadil Faris, Alanazi, Mohammed M., Noamaan, Mahmoud A., Murugesan, Sankaranarayanan, Amran, Syazwani Itri, Bhat, Ajmal R., Jamalis, Joazaizulfazli |
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Format: | Article |
Language: | English |
Published: |
MDPI
2023
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Subjects: | |
Online Access: | http://eprints.utm.my/106207/1/SyazwaniItriAmran2023_DiscoveryofNovelCoumarinSchiffBase.pdf http://eprints.utm.my/106207/ http://dx.doi.org/10.3390/ph16070971 |
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