Quantification of Dynamic 11C-Phenytoin PET Studies
The overexpression of P-glycoprotein (Pgp) is thought to be an important mechanism of pharmacoresistance in epilepsy. Recently, 11C-phenytoin has been evaluated preclinically as a tracer for Pgp. The aim of the present study was to assess the optimal plasma kinetic model for quantification of 11...
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Main Authors: | Mansor, Mohd Syahir, Boellaard, Ronald, Froklage, Femke E., Bakker, Esther D.M., Yaqub, Maqsood, Voskuyl, Rob A., Schwarte, Lothar A., Verbeek, Joost, Windhorst, Albert D., Lammertsma, Adriaan |
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Format: | Article |
Language: | English |
Published: |
Society of Nuclear Medicine
2015
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Subjects: | |
Online Access: | http://eprints.usm.my/37523/1/syahirnuclmedpostprint.pdf http://eprints.usm.my/37523/ http://jnm.snmjournals.org/content/56/9/1372.short |
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